Low Serum Levels of DKK2 Predict Incident Low‐Impact Fracture in Older Women

Volume: 3, Issue: 7
Published: Mar 28, 2019
Abstract
There are currently no robust noninvasive markers of fragility fractures. Secreted frizzled related protein-1 (sFRP-1), dickkopf-related protein 1 (DKK1) and DKK2, and sclerostin (SOST) inhibit Wnt signaling and interfere with osteoblast-mediated bone formation. We evaluated associations of serum levels of sFRP-1, DKK1, DKK2, and SOST with incident low-impact fracture and BMD in 828 women aged ≥65 years from EpiDoC, a longitudinal...
Paper Details
Title
Low Serum Levels of DKK2 Predict Incident Low‐Impact Fracture in Older Women
Published Date
Mar 28, 2019
Volume
3
Issue
7
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