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Epidemiology of Depression in Patients with Psoriasis: A Nationwide Population-based Cross-sectional Study

Published on Jan 1, 2019in Acta Dermato-venereologica3.531
· DOI :10.2340/00015555-3145
Stephen Chu-Sung Hu13
Estimated H-index: 13
,
Gwo-Shing Chen24
Estimated H-index: 24
,
Hung-Pin Tu1
Estimated H-index: 1
Abstract
: The epidemiology of depression in patients with psoriasis has not been well defined in the Asian population. This study evaluated the epidemiological features of, and risk factors for, depression among patients with psoriasis in Taiwan. A nationwide population-based cross-sectional study was undertaken using the National Health Insurance Research Database. This study included 17,086 patients with psoriasis and 1,607,242 patients from the general population. The prevalence of depression in patients with psoriasis was 11.52%, while the prevalence of depression in the general population was 7.73% (prevalence ratio 1.49, 95% confidence interval 1.43-1.55). Multivariable analysis showed that, in patients with psoriasis, risk factors associated with depression were: age 20-50 years, female sex, low income, and major comorbid diseases, including liver cirrhosis, renal disease, cardiovascular disease and cerebrovascular disease. Therefore, the prevalence of depression is higher in patients with psoriasis, particularly in young and middle-aged women with low income and major comorbidities.
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BACKGROUND: Sex and gender may affect disease prevalence, adverse effects and response to therapy. AIM: To analyse sex- and gender differences in psoriasis outpatients. METHODS: A cross-sectional study was conducted at IDI-IRCCS, Rome, over a 3-year period. 3023 psoriasis patients were enrolled. Anthropometric and demographic characteristics were recorded, and a dermatologist evaluated the clinical severity of disease. Quality of life questionnaires were collected. Univariate and multivariate an...
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#1Ying-Xiu Dai (NYMU: National Yang-Ming University)H-Index: 5
#2Chih-Chiang Chen (NYMU: National Yang-Ming University)H-Index: 23
Last. Mu-Hong Chen (NYMU: National Yang-Ming University)H-Index: 26
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BACKGROUND: Previous studies have shown that patients with psoriasis have a higher risk of depression. However, the risk of major depressive disorder (MDD) among unaffected siblings of psoriasis probands remains unknown. This study aimed to investigate the risk of MDD among probands with psoriasis and unaffected siblings. METHODS: We selected subjects from the National Health Insurance Research Database (NHIRD) in Taiwan. Subjects were followed up from 01 January 1996 until a diagnosis of MDD, d...
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#1Arsh Patel (Wake Forest University)H-Index: 2
#2Mohammad Jafferany (CMU: Central Michigan University)H-Index: 11
Last. Bárbara Roque Ferreira (University of Lisbon)H-Index: 4
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Chronic dermatologic disease with visible lesions may result in lifelong psychosocial distress among afflicted patients. In this chapter, we present factors that may result in certain individuals to develop psychiatric conditions like depression and anxiety, secondary to a dermatologic disease. Specific patient-centered contributors like body-image satisfaction, disease-related characteristics (size, appearance, chronicity), and external sociocultural aspects are discussed. Further, we delve int...
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#1José M. Martínez-Ortega (UGR: University of Granada)H-Index: 11
Last. Manuel Gurpegui (UGR: University of Granada)H-Index: 25
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Abstract Objective To compare quality of life (QoL), anxiety and depressive symptoms, alcohol consumption and other correlates between patients with psoriasis and controls; and to identify features of psoriasis associated with lower levels of QoL. Method Case-control study including 70 subjects with moderate-severe psoriasis and 140 controls without psoriasis. All participants answered the Short Form Health Survey (SF-36), with physical and mental component scores of quality of life, and the Hos...
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