The genetic requirements of fatty acid import by Mycobacterium tuberculosis within macrophages
Abstract
Mycobacterium tuberculosis (Mtb) imports and metabolizes fatty acids to maintain infection within human macrophages. Although this is a well-established paradigm, the bacterial factors required for fatty acid import are poorly understood. Previously, we found that LucA and Mce1 are required for fatty acid import in Mtb (Nazarova et al., 2017). Here, we identified additional Mtb mutants that have a reduced ability to import a fluorescent fatty...
Paper Details
Title
The genetic requirements of fatty acid import by Mycobacterium tuberculosis within macrophages
Published Date
Feb 8, 2019
Journal
Volume
8
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