Classical monocytes maintain ex vivo glycolytic metabolism and early but not later inflammatory responses in older adults
Abstract
Inflammaging is a condition of chronic low-grade inflammation due to the aging process and is associated with a variety of chronic diseases. Monocytes are innate immune cells which contribute to inflammation and are dysregulated during aging, demonstrated reduced phagocytosis, increased inflammation, and alterations in subset proportions. Metabolism is known to determine immune cell function, with quiescent and anti-inflammatory cells primarily...
Paper Details
Title
Classical monocytes maintain ex vivo glycolytic metabolism and early but not later inflammatory responses in older adults
Published Date
Jan 26, 2019
Journal
Volume
16
Issue
1
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Notes
History