Peroxisome-associated Sgroppino links fat metabolism with survival after RNA virus infection in Drosophila
Abstract
The fruit fly Drosophila melanogaster is a valuable model organism for the discovery and characterization of innate immune pathways, but host responses to virus infection remain incompletely understood. Here, we describe a novel player in host defense, Sgroppino (Sgp). Genetic depletion of Sgroppino causes hypersensitivity of adult flies to infections with the RNA viruses Drosophila C virus, cricket paralysis virus, and Flock House virus....
Paper Details
Title
Peroxisome-associated Sgroppino links fat metabolism with survival after RNA virus infection in Drosophila
Published Date
Feb 14, 2019
Journal
Volume
9
Issue
1
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