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Choosing the Method of Crystallization to Obtain Optimal Results

Published on Feb 19, 2019
· DOI :10.3390/cryst9020106
Lata Govada13
Estimated H-index: 13
,
Naomi E. Chayen33
Estimated H-index: 33
Abstract
Anyone who has ever attempted to crystallise a protein or other biological macromolecule has encountered at least one, if not all of the following scenarios: No crystals at all, tiny low quality crystals; phase separation; amorphous precipitate and the most frustrating; large, beautiful crystals that do not diffract at all. In this paper we review a number of simple ways to overcome such problems, which have worked well in our hands and in other laboratories. It brings together information that has been dispersed in various publications and lectures over the years and includes further information that has not been previously published.
  • References (32)
  • Citations (2)
References32
Newest
#1Linda Johansson (SC: University of Southern California)H-Index: 4
#2Benjamin Stauch (SC: University of Southern California)H-Index: 7
Last.Vadim Cherezov (SC: University of Southern California)H-Index: 60
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#1Bahige G. Abdallah (ASU: Arizona State University)H-Index: 6
#2Shatabdi Roy-Chowdhury (ASU: Arizona State University)H-Index: 12
Last.Alexandra RosH-Index: 26
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#1Arne Meyer (University of Lübeck)H-Index: 9
#2Karsten Dierks (University of Lübeck)H-Index: 10
Last.Christian Betzel (UHH: University of Hamburg)H-Index: 38
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#1Fermín Otálora (UGR: University of Granada)H-Index: 22
#2Jose A. Gavira (UGR: University of Granada)H-Index: 23
Last.Juan Manuel García-Ruiz (UGR: University of Granada)H-Index: 32
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