Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes
Abstract
The purpose of this study was to determine important genes, functions, and networks contributing to the pathobiology of cerebral cavernous malformation (CCM) from transcriptomic analyses across 3 species and 2 disease genotypes. Sequencing of RNA from laser microdissected neurovascular units of 5 human surgically resected CCM lesions, mouse brain microvascular endothelial cells, Caenorhabditis elegans with induced Ccm gene loss, and their...
Paper Details
Title
Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes
Published Date
Feb 7, 2019
Journal
Volume
4
Issue
3
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