Synthesis, characterization and biological evaluation of Co(III) complexes with quinolone drugs

Volume: 193, Pages: 94 - 105
Published: Apr 1, 2019
Abstract
Nine novel cobalt(III) ternary complexes bearing 4N donor ligands (tris(2-aminoethyl)amine (tren) or tris(2-methylpyridyl)amine (tpa)) and (fluoro)quinolones (quinH) with antibacterial and potential antitumor activity have been synthesized, characterized and screened in various biological assays. The molecular structures of [Co(tpa)(nal)](PF6)2 (3) and [Co(tpa)(nor)(Co(tpa)(norH)](PF6)3(Cl)2∙5MeOH (8) (nal = deprotonated form of nalidixic acid,...
Paper Details
Title
Synthesis, characterization and biological evaluation of Co(III) complexes with quinolone drugs
Published Date
Apr 1, 2019
Volume
193
Pages
94 - 105
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