In vivo assessment of increased oxidation of branched-chain amino acids in glioblastoma
Abstract
Altered branched-chain amino acids (BCAAs) metabolism is a distinctive feature of various cancers and plays an important role in sustaining tumor proliferation and aggressiveness. Despite the therapeutic and diagnostic potentials, the role of BCAA metabolism in cancer and the activities of associated enzymes remain unclear. Due to its pivotal role in BCAA metabolism and rapid cellular transport, hyperpolarized 13 C-labeled α-ketoisocaproate...
Paper Details
Title
In vivo assessment of increased oxidation of branched-chain amino acids in glioblastoma
Published Date
Jan 23, 2019
Journal
Volume
9
Issue
1
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