Effect of TCF7L2 polymorphism on pancreatic hormones after exenatide in type 2 diabetes

Volume: 11, Issue: 1
Published: Jan 25, 2019
Abstract
Glucagon-like peptide 1 (GLP-1) stimulates insulin secretion and reduces blood glucose in type 2 diabetes mellitus (T2DM). TCF7L2 rs7903146 polymorphism has been associated with decreased insulin secretion, reduced GLP-1 action, and possible impaired peripheral insulin sensitivity. To evaluate the postprandial pancreatic hormone response in patients with T2DM carriers of the TCF7L2 variant rs7903146 (CT/TT) compared with noncarriers of this...
Paper Details
Title
Effect of TCF7L2 polymorphism on pancreatic hormones after exenatide in type 2 diabetes
Published Date
Jan 25, 2019
Journal
Volume
11
Issue
1
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