Identifying a potential biomarker for primary focal segmental glomerulosclerosis and its association with recurrence after transplantation

Background We investigated circulating levels of individual soluble urokinase plasminogen activation receptor (su PAR ) forms to determine if specific circulating fragments of su PAR ( II ‐ III ) and (I) can better serve as clinical biomarkers for focal segmental glomerulosclerosis ( FSGS ) and the risk of recurrence after transplantation. Materials and Methods Serum levels of intact su PAR and its cleaved forms were measured with two assays,...