The association of Native American and European ancestry with Atopy, Asthma and Lung function in Asthma Cases and Controls from Peru

Given the role ancestry plays in asthma health disparities, we sought to identify the impact of ancestry on asthma prevalence, atopy (> 0.1ku/L to one or more of animal, mold or dust mix using ImmunoCAP), and lung function in two adjacent communities from Peru. Genotyping was performed on 436 asthmatics and 291 controls aged 9-19 years using the Illumina MEGA-chip. Ancestry deconvolution was performed using ADMIXTURE to estimate the genome-wide...