Cloning of a gene-edited macaque monkey by somatic cell nuclear transfer

Volume: 6, Issue: 1, Pages: 101 - 108
Published: Jan 1, 2019
Abstract
Cloning of macaque monkeys by somatic cell nucleus transfer (SCNT) allows the generation of monkeys with uniform genetic backgrounds that are useful for the development of non-human primate models of human diseases. Here, we report the feasibility of this approach by SCNT of fibroblasts from a macaque monkey (Macaca fascicularis), in which a core circadian transcription factor BMAL1 was knocked out by clustered regularly interspaced short...
Paper Details
Title
Cloning of a gene-edited macaque monkey by somatic cell nuclear transfer
Published Date
Jan 1, 2019
Volume
6
Issue
1
Pages
101 - 108
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