Regulation of PKD2L1 by Calcium Effectors

Architecture of a tissue is determined by the function and positioning of cilia. Cilia is a membrane bound compartment, projected like antenna from the periphery of cell, acting as a sensor for external stimuli. Ciliary malfunction leads to defects in tissue organization, developmental anomalies and sensory reception, which are collectively called as ciliopathies. One of the most common and life-threatening ciliopathy is autosomal dominant...