Pathway Based Analysis of Mutation Data Is Efficient for Scoring Target Cancer Drugs
Abstract
Despite the significant achievements in chemotherapy, cancer remains one of the leading causes of death. Target therapy revolutionized this field, but efficiencies of target drugs show dramatic variation among individual patients. Personalization of target therapies remains, therefore, a challenge in oncology. Here, we proposed molecular pathway-based algorithm for scoring of target drugs using high throughput mutation data to personalize their...
Paper Details
Title
Pathway Based Analysis of Mutation Data Is Efficient for Scoring Target Cancer Drugs
Published Date
Jan 23, 2019
Journal
Volume
10
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