A Pooled Analysis of Survival By Defibrotide (DF) Timing of Initiation in Adults with Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) Following Hematopoietic Stem Cell Transplant (HSCT)

Volume: 25, Issue: 3, Pages: S129 - S130
Published: Mar 1, 2019
Abstract
IntroductionHepatic VOD/SOS is a potentially life-threatening complication of HSCT or nontransplant chemotherapy. VOD/SOS with multi-organ dysfunction (MOD; eg, renal or pulmonary) may be associated with >80% mortality. DF is approved to treat hepatic VOD/SOS with renal or pulmonary dysfunction post-HSCT in the US and Canada, and severe hepatic VOD/SOS post-HSCT in patients aged >1 month in the EU.MethodsData from the international compassionate...
Paper Details
Title
A Pooled Analysis of Survival By Defibrotide (DF) Timing of Initiation in Adults with Veno-Occlusive Disease/Sinusoidal Obstruction Syndrome (VOD/SOS) Following Hematopoietic Stem Cell Transplant (HSCT)
Published Date
Mar 1, 2019
Volume
25
Issue
3
Pages
S129 - S130
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