Original paper

RNase HIII Is Important for Okazaki Fragment Processing in Bacillus subtilis

Volume: 201, Issue: 7
Published: Apr 1, 2019
Abstract
All cells are required to resolve the different types of RNA-DNA hybrids that form in vivo . When RNA-DNA hybrids persist, cells experience an increase in mutation rate and problems with DNA replication. Okazaki fragment synthesis on the lagging strand requires an RNA primer to begin synthesis of each fragment. The mechanism of RNA removal from Okazaki fragments remains unknown in bacteria that lack RNase HI. We examined Okazaki fragment...
Paper Details
Title
RNase HIII Is Important for Okazaki Fragment Processing in Bacillus subtilis
Published Date
Apr 1, 2019
Volume
201
Issue
7
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