Functional variation at an expressed MHC class IIβ locus associates with Ranavirus infection intensity in larval anuran populations
Abstract
Infectious diseases are causing catastrophic losses to global biodiversity. Iridoviruses in the genus Ranavirus are among the leading causes of amphibian disease-related mortality. Polymorphisms in major histocompatibility complex (MHC) genes are significantly associated with variation in amphibian pathogen susceptibility. MHC genes encode two classes of polymorphic cell-surface molecules that can recognize and bind to diverse pathogen peptides....
Paper Details
Title
Functional variation at an expressed MHC class IIβ locus associates with Ranavirus infection intensity in larval anuran populations
Published Date
Feb 13, 2019
Journal
Volume
71
Issue
4
Pages
335 - 346
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