Establishing a generalized polyepigenetic biomarker for tobacco smoking
Abstract
Large-scale epigenome-wide association meta-analyses have identified multiple ‘signatures’’ of smoking. Drawing on these findings, we describe the construction of a polyepigenetic DNA methylation score that indexes smoking behavior and that can be utilized for multiple purposes in population health research. To validate the score, we use data from two birth cohort studies: The Dunedin Longitudinal Study, followed to age-38 years, and the...
Paper Details
Title
Establishing a generalized polyepigenetic biomarker for tobacco smoking
Published Date
Feb 15, 2019
Journal
Volume
9
Issue
1
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