Proteome-wide onco-proteogenomic somatic variant identification in ER-positive breast cancer
Abstract
Recent advances in mass spectrometric instrumentation and bioinformatics have critically contributed to the field of proteogenomics. Nonetheless, whether that integrative approach has reached the point of maturity to effectively reveal the flow of genetic variants from DNA to proteins still remains elusive. The objective of this study was to detect somatically acquired protein variants in breast cancer specimens for which full genome and...
Paper Details
Title
Proteome-wide onco-proteogenomic somatic variant identification in ER-positive breast cancer
Published Date
Apr 1, 2019
Journal
Volume
66
Pages
63 - 75
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Notes
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