Recognition of HER2 expression in hepatocellular carcinoma and its significance in postoperative tumor recurrence
Abstract
Background The ERBB2 oncogene hypothesis is challenged in hepatocellular carcinoma (HCC) with the conflicting evidences of human epidermal growth factor receptor 2 (HER2) overexpression. HER2 could be a new target as a treatment option for HCC as well as tumor recurrence after surgery. HER2 in HCC biology needs further explorations. Methods Clinical and mRNA data of HCC patients were obtained from TCGA HCC cohort, GSE89377 and GSE115018. Western...
Paper Details
Title
Recognition of HER2 expression in hepatocellular carcinoma and its significance in postoperative tumor recurrence
Published Date
Feb 4, 2019
Journal
Volume
8
Issue
3
Pages
1269 - 1278
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