Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation
Abstract
Increased free thyroxine (FT4) and decreased thyrotropin are associated with increased risk of atrial fibrillation (AF) in observational studies, but direct involvement is unclear.To evaluate the potential direct involvement of thyroid traits on AF.Study-level mendelian randomization (MR) included 11 studies, and summary-level MR included 55 114 AF cases and 482 295 referents, all of European ancestry.Genomewide significant variants were used as...
Paper Details
Title
Assessment of the Relationship Between Genetic Determinants of Thyroid Function and Atrial Fibrillation
Published Date
Feb 1, 2019
Journal
Volume
4
Issue
2
Pages
144 - 144
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