Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin
Abstract
Myelin serves as an axonal insulator that facilitates rapid nerve conduction along axons. By transmission electron microscopy, a healthy myelin sheath comprises compacted membrane layers spiraling around the cross-sectioned axon. Previously we identified the assembly of septin filaments in the innermost non-compacted myelin layer as one of the latest steps of myelin maturation in the central nervous system (CNS) (Patzig et al., 2016). Here we...
Paper Details
Title
Anillin facilitates septin assembly to prevent pathological outfoldings of central nervous system myelin
Published Date
Jan 23, 2019
Journal
Volume
8
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