Abstract B41: Modeling bone development and cancer predisposition in Diamond Blackfan anemia (DBA)
Abstract
DBA is an inherited bone marrow failure syndrome characterized by pure red cell aplasia, congenital physical anomalies, and cancer predisposition, in particular an increased incidence of osteogenic sarcoma (O:E 42.44). In order to investigate the mechanism of defective bone development and ultimately oncogenesis, we used an in vitro model consisting of mouse embryonic stem cells gene trapped for the Ribosomal Protein 19 gene (Rps19) and...
Paper Details
Title
Abstract B41: Modeling bone development and cancer predisposition in Diamond Blackfan anemia (DBA)
Published Date
Oct 1, 2018
Journal
Volume
78
Issue
19_Supplement
Pages
B41 - B41
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