Challenges in the management of septic shock: a narrative review

While guidelines provide important information on how to approach a patient in septic shock, null challenges remain for the management of these patients. In this narrative review, the panel discusses the challenges in identifying the right hemodynamic target, optimization of fluid therapy, selection of vasopressor agents, identification of patients who may benefit from inotropic agents or on the contrary beta-blockade, and use of steroids. The...