Altered cord blood mitochondrial DNA content and pregnancy lead exposure in the PROGRESS cohort
Abstract
Lead (Pb) crosses the placenta and can cause oxidative stress, reduced fetal growth and neurological problems. The principal source of oxidative stress in human cells is mitochondria. Therefore, disruption of normal mitochondrial function during pregnancy may represent a primary mechanism behind the adverse effects of lead. We sought to assess the association of Pb exposure during pregnancy with mitochondrial DNA (mtDNA) content, a sensitive...
Paper Details
Title
Altered cord blood mitochondrial DNA content and pregnancy lead exposure in the PROGRESS cohort
Published Date
Apr 1, 2019
Journal
Volume
125
Pages
437 - 444
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