Liposome formulations of o-carborane for the boron neutron capture therapy of cancer
Abstract
Based on the promise of liposomes as convenient vehicles for the transport of boronated agents for the boron neutron capture therapy (BCNT) of cancer, this paper reports a method for the formulation and characterisation of stable o-carborane-loaded liposomes (ca. 80-100 nm) of dipalmitoyl-phosphatidylcholine (DPPC) or 1,2-distearol-sn-glycerol-3-phosphocholine (DSPC). Preliminary pharmaceutical characterisation experiments have demonstrated the...
Paper Details
Title
Liposome formulations of o-carborane for the boron neutron capture therapy of cancer
Published Date
Apr 1, 2019
Journal
Volume
247
Pages
25 - 33
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