The neutralization of heparan sulfate by heparin-binding copolymer as a potential therapeutic target
Abstract
Besides regulating ligand-receptor and cell-cell interactions, heparan sulfate (HS) may participate in the development of many diseases, such as cancer, bacterial or viral infections, and their complications, like bleeding or inflammation. In these cases, the neutralization of HS could be a potential therapeutic target. The heparin-binding copolymer (HBC, PEG41-PMAPTAC53) was previously reported by us as a fully synthetic compound for efficient...
Paper Details
Title
The neutralization of heparan sulfate by heparin-binding copolymer as a potential therapeutic target
Published Date
Jan 1, 2019
Journal
Volume
9
Issue
6
Pages
3020 - 3029
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