Manipulation-induced hypoalgesia in musculoskeletal pain populations: a systematic critical review and meta-analysis

Manipulation-induced hypoalgesia (MIH) represents reduced pain sensitivity following joint manipulation, and has been documented in various populations. It is unknown, however, whether MIH following high-velocity low-amplitude spinal manipulative therapy is a specific and clinically relevant treatment effect. This systematic critical review with meta-analysis investigated changes in quantitative sensory testing measures following high-velocity...