Roux-en-Y Gastric Bypass Is Associated With Hyperinsulinemia But Not Increased Maximal β-Cell Function

Roux-en-Y gastric bypass (RYGB) is associated with postprandial hyperinsulinemia.This study assessed whether increased blood insulin levels may be due to an increase in maximal β-cell function.We performed a cross-sectional study at Columbia University Medical Center, New York, New York. Subjects without a history of diabetes were studied after surgery (n = 12) and were compared with nonsurgical controls (n = 10) who were mean matched for body...