Design of Microparticulated Salbutamol Sulfate PH Sensitive Pulsatile Delivery System for Chronotherapy of Nocturnal Asthma

Volume: 12, Issue: 04
Published: Feb 4, 2019
Abstract
Objective: The main objective of this study was to prepare and evaluate pH-dependent chronotherapeutic drug delivery of salbutamol using chitosan (CS) and Eudragit polymers. Materials and Methods: Chronotherapeutic microparticles were prepared in two steps, in first step core CS microparticles were prepared using glutaraldehyde cross-linking and in the second step entrapped within Eudragit S 100 and Eudragit L 100. Results: The microparticles...
Paper Details
Title
Design of Microparticulated Salbutamol Sulfate PH Sensitive Pulsatile Delivery System for Chronotherapy of Nocturnal Asthma
Published Date
Feb 4, 2019
Volume
12
Issue
04
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