Intrahepatic fibrin(ogen) deposition drives liver regeneration after partial hepatectomy in mice and humans
Abstract
Platelets play a pivotal role in stimulating liver regeneration after partial hepatectomy in rodents and humans. Liver regeneration in rodents is delayed when platelets are inhibited. However, the exact mechanisms whereby platelets accumulate and promote liver regeneration remain uncertain. Thrombin-dependent intrahepatic fibrin(ogen) deposition was recently reported after partial hepatectomy (PHx) in mice, but the role of fibrin(ogen) deposits...
Paper Details
Title
Intrahepatic fibrin(ogen) deposition drives liver regeneration after partial hepatectomy in mice and humans
Published Date
Mar 14, 2019
Journal
Volume
133
Issue
11
Pages
1245 - 1256
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