Review paper
Structure and function of extracellular O-GlcNAc
Abstract
Extracellular O-GlcNAc is a unique modification restricted to the epidermal growth factor (EGF) domain-containing glycoproteins. This O-GlcNAcylation is catalyzed by the EGF-domain specific O-GlcNAc transferase (EOGT), which is localized in the lumen of endoplasmic reticulum. In humans, EOGT is one of the causative genes of a congenital disease, Adams-Oliver syndrome. EOGT is highly expressed in endothelial cells and regulates vascular...
Paper Details
Title
Structure and function of extracellular O-GlcNAc
Published Date
Jun 1, 2019
Volume
56
Pages
72 - 77
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