Comparison of three heterochromatin protein 1 homologs of Drosophila

Heterochromatin protein 1 (HP1) is an epigenetic regulator of chromatin structure and genome function in eukaryotes. Despite shared features, most eukaryotes have minimum three HP1 homologs with differential localization patterns and functions. Most studies focus on Drosophila HP1a, and little is known about the properties of HP1b and HP1c. To determine the features of the three HP1 homologs, we performed the first comprehensive comparative...