Review paper
Tails of a Super Histone
Abstract
Diffuse intrinsic brain stem gliomas (DIPGs) with characteristic K27M mutation of H3.3 are lethal and poorly understood childhood cancers. In this issue of Cancer Cell, Larson et al. exploit a unique murine DIPG model with inducible, endogenous K27M expression to reveal insights into mechanisms of K27M-mediated transformation in DIPG. Diffuse intrinsic brain stem gliomas (DIPGs) with characteristic K27M mutation of H3.3 are lethal and poorly...
Paper Details
Title
Tails of a Super Histone
Published Date
Jan 1, 2019
Journal
Volume
35
Issue
1
Pages
7 - 9
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Notes
History