Direct Metal‐Free Preparation of Functionalizable Polylactic Acid‐Ethisterone Conjugates in a One‐Pot Approach
Abstract
A series of polylactic acid (PLA) conjugates (PLA‐ES) are synthesized via direct melt polycondensation (DMP) of lactic acid (LA) with ethisterone (ES) in the presence of 0.3 wt% toluenesulfonic acid at 160 °C for 6 h. The drug content of PLA conjugates can be simply adjustable. Further functionalization via Click chemistry is also achieved to extend the biomedicine application of biopolymer based drug...
Paper Details
Title
Direct Metal‐Free Preparation of Functionalizable Polylactic Acid‐Ethisterone Conjugates in a One‐Pot Approach
Published Date
Jan 18, 2019
Volume
220
Issue
5
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