Lower total cerebral arterial flow contributes to cognitive performance in multiple sclerosis patients

Background: The cognitive performance in multiple sclerosis (MS) patients declines with aging, longer disease duration, and possibly cardiovascular comorbidities. Objectives: We investigated whether lower total cerebral arterial blood flow (CABF) measured at the level of the carotid and vertebral arteries may contribute to worse cognitive performance in 132 MS patients and 47 healthy controls. Methods: Total CABF was evaluated with extracranial...