Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway
Abstract
The importance of gut microbiota in human health and pathophysiology is undisputable. Despite the abundance of metagenomics data, the functional dynamics of gut microbiota in human health and disease remain elusive. Urolithin A (UroA), a major microbial metabolite derived from polyphenolics of berries and pomegranate fruits displays anti-inflammatory, anti-oxidative, and anti-ageing activities. Here, we show that UroA and its potent synthetic...
Paper Details
Title
Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway
Published Date
Jan 9, 2019
Journal
Volume
10
Issue
1
Pages
89 - 89
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History