Treatment of obesity in older persons-A systematic review.

Published on Apr 1, 2019in Obesity Reviews8.192
· DOI :10.1111/obr.12815
Cilla Haywood7
Estimated H-index: 7
(University of Melbourne),
Priya Sumithran10
Estimated H-index: 10
(University of Melbourne)
The study aims to systematically review the available evidence regarding weight loss interventions (lifestyle, surgical, and pharmacological) for obesity in adults aged over 60 years. A search of prospective, randomized studies took place in January 2018, on Medline (Web of Science) and PubMed databases. Search terms included the following: elderly, obese, hypocaloric, pharmacotherapy, and bariatric surgery. Abstracts were screened for eligibility. A total of 256 publications regarding lifestyle interventions were identified; of these, 69 studies were eligible. As no eligible studies were identified for pharmacotherapy or bariatric surgery, the search was broadened to include non‐ randomized studies. Four pharmacotherapy and 66 surgery studies were included. Lifestyle intervention had similar weight loss efficacy in older compared with younger people, with positive effects on a number of relevant outcomes, including physical function and cardiovascular parameters. There was little data regarding obesity pharmacotherapy in older persons. The available data for bariatric surgery indicate comparable weight loss and resolution of type 2 diabetes, with similar or slightly higher complication rates in older compared with younger people. Older age alone should not be considered a contraindication to intensive lifestyle or surgical intervention for obesity. There are insufficient data to guide clinical decisions regarding obesity pharmacotherapy in older people.
  • References (144)
  • Citations (1)
#1Vasilios Kotsis (A.U.Th.: Aristotle University of Thessaloniki)H-Index: 20
#2Jens Jordan (MHH: Hannover Medical School)H-Index: 60
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Obesity is a key factor for cardiovascular diseases and complications. Obesity is associated with hypertension, dyslipidemia and type II diabetes, which are the major predictors of cardiovascular disease in the future. It predisposes for atrial fibrillation, heart failure, sudden cardiac death, rena
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#2Madalena RamosH-Index: 4
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#1Katherine D. Gray (NewYork–Presbyterian Hospital)H-Index: 6
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#1Cilla Haywood (University of Melbourne)H-Index: 7
#2Luke A. Prendergast (La Trobe University)H-Index: 14
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#2Yukari Maeda (Chiba University)H-Index: 1
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Aim Laparoscopic sleeve gastrectomy (LSG) has proven to be the most effective strategy for the treatment of morbid obesity, however its efficacy and safety in an aging population has not yet been confirmed. In this study, we evaluated the effectiveness and safety of LSG in elderly obese Japanese patients. Methods Three obese individuals aged >60 years and 11 obese individuals aged <60 years who underwent LSG were enrolled. Pre- and postoperative changes after at least 12 months were examined, in...
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#1Robert A. Casillas (WLAC: West Los Angeles College)H-Index: 3
#2Benjamin Kim (WLAC: West Los Angeles College)H-Index: 1
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Abstract Background Most bariatric studies in older adult patients have focused on older operations with limited follow-up and equivocal results. Objectives To compare weight loss and safety in patients ages≥65 years undergoing laparoscopic sleeve gastrectomy (SG) and laparoscopic Roux-en-Y gastric bypass (LRYGB). Setting Nine different bariatric surgery centers with 23 surgeons serving over 30,000 bariatric patients. Methods Participants were≥65 years who had a SG or LRYGB between January 1, 20...
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#1Damien Bergeat (University of Rennes)H-Index: 8
#2David LechauxH-Index: 1
Last. Vianney BouyguesH-Index: 1
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Background Laparoscopic bariatric surgery (LBS) in older obese patients remains debated regarding postoperative outcomes.
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#1Chetan ParmarH-Index: 14
#2Kamal K. MahawarH-Index: 21
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#1Andrés Navarrete (Universidad del Desarrollo)H-Index: 2
#2Ricard CorcellesH-Index: 17
Last. Antonio M. LacyH-Index: 60
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Abstract Background Advanced age is considered to be a relative contraindication to bariatric surgery because of increased perioperative risk and suboptimal excess weight loss. Objectives The aim of this study was to analyze the safety and effectiveness of the sleeve gastrectomy (SG) procedure in a cohort of elderly patients (aged≥60 yr) compared with younger patients (aged Setting Hospital clinic, Barcelona, Spain. Methods A retrospective analysis of all cases of SG in patients≥60 years old bet...
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#2Rebecca McClure (University of the Sunshine Coast)H-Index: 2
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