Sox11-modified mesenchymal stem cells accelerate cartilage defect repair in SD rats

Volume: 376, Issue: 2, Pages: 247 - 255
Published: Jan 8, 2019
Abstract
Cartilage has a limited capacity to heal. Previously, we have shown that overexpression of Sox11 in rMSCs (Rat Mesenchymal Stem Cells) by lentivirus-mediated gene transfer leads to enhanced tri-lineage differentiation and accelerated bone formation in fracture model of rats. We observed that the fracture repair in the rats that received Sox11-modified rMSCs injection proceeded through an endochondral ossification process much faster than those...
Paper Details
Title
Sox11-modified mesenchymal stem cells accelerate cartilage defect repair in SD rats
Published Date
Jan 8, 2019
Volume
376
Issue
2
Pages
247 - 255
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