Long-term functional and structural preservation of precision-cut human myocardium under continuous electromechanical stimulation in vitro
Abstract
In vitro models incorporating the complexity and function of adult human tissues are highly desired for translational research. Whilst vital slices of human myocardium approach these demands, their rapid degeneration in tissue culture precludes long-term experimentation. Here, we report preservation of structure and performance of human myocardium under conditions of physiological preload, compliance, and continuous excitation. In biomimetic...
Paper Details
Title
Long-term functional and structural preservation of precision-cut human myocardium under continuous electromechanical stimulation in vitro
Published Date
Jan 10, 2019
Journal
Volume
10
Issue
1
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