Multiscale characterization of heart failure
Abstract
Dilated cardiomyopathy is a progressive irreversible disease associated with contractile dysfunction and heart failure. During dilated cardiomyopathy, elevated diastolic wall strains trigger mechanotransduction pathways that initiate the addition of sarcomeres in series and an overall increase in myocyte length. At the whole organ level, this results in a chronic dilation of the ventricles, an increase in end diastolic and end systolic volumes,...
Paper Details
Title
Multiscale characterization of heart failure
Published Date
Mar 1, 2019
Journal
Volume
86
Pages
66 - 76
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Notes
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