LHX2- and LDB1-mediated trans interactions regulate olfactory receptor choice
Abstract
The genome is partitioned into topologically associated domains and genomic compartments with shared chromatin valence. This architecture is constrained by the DNA polymer, which precludes interactions between genes on different chromosomes. Here we report a marked divergence from this pattern of nuclear organization that occurs in mouse olfactory sensory neurons. Chromatin conformation capture using in situ Hi-C on fluorescence-activated...
Paper Details
Title
LHX2- and LDB1-mediated trans interactions regulate olfactory receptor choice
Published Date
Jan 1, 2019
Journal
Volume
565
Issue
7740
Pages
448 - 453
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Notes
History