An AR-ERG transcriptional signature defined by long-range chromatin interactomes in prostate cancer cells
Abstract
The aberrant activities of transcription factors such as the androgen receptor (AR) underpin prostate cancer development. While the AR cis -regulation has been extensively studied in prostate cancer, information pertaining to the spatial architecture of the AR transcriptional circuitry remains limited. In this paper, we propose a novel framework to profile long-range chromatin interactions associated with AR and its collaborative transcription...
Paper Details
Title
An AR-ERG transcriptional signature defined by long-range chromatin interactomes in prostate cancer cells
Published Date
Jan 3, 2019
Journal
Volume
29
Issue
2
Pages
223 - 235
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