Cancer Stem Cells: The Architects of the Tumor Ecosystem
Abstract
Cancer stem cells (CSCs) proactively remodel their microenvironment to maintain a supportive niche. Viewed through the lens of an ecosystem, numerous tumor components have multi-directional interactions involving CSCs, supporting the complexity of tumors to maintain growth in a dynamic host. In this Perspective, we discuss how CSCs are active architects of their microenvironment and drive interactions with other tumor components, such as immune...
Paper Details
Title
Cancer Stem Cells: The Architects of the Tumor Ecosystem
Published Date
Jan 1, 2019
Journal
Volume
24
Issue
1
Pages
41 - 53
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