Comparative genomics and transcriptomics of host–pathogen interactions in insects: evolutionary insights and future directions

Classical evolutionary studies of protein-coding genes have established that genes in the canonical immune system are often among the most rapidly evolving within and between species. As more genomes and transcriptomes across insects are sequenced, it is becoming clear that duplications and losses of immune genes are also a likely consequence of host–pathogen interactions. Furthermore, particular species respond to diverse pathogenic challenges...