Secreted Frizzled-related protein 4 inhibits the regeneration of hair follicles

PeerJ2.70
Volume: 6, Pages: e6153 - e6153
Published: Jan 4, 2019
Abstract
Secreted Frizzled-related Protein 4 (sFRP4) belongs to Wnt inhibitors. Previously, we reported that sFRP4 inhibited the differentiation of melanocyte. Here, by using of immunostaining, we showed that sFRP4 is expressed in both human and mouse hair follicles, especially in the outer root sheath and inner root sheath. To reveal the role of sFRP4 in hair follicle growth and hair cycle, we induced synchronized hair cycle in the dorsal skin of mice...
Paper Details
Title
Secreted Frizzled-related protein 4 inhibits the regeneration of hair follicles
Published Date
Jan 4, 2019
Journal
Volume
6
Pages
e6153 - e6153
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