Chlorin e6 and halogen light as a sebostatic photomedicine modulates linoleic acid-induced lipogenesis

Chlorin e6-mediated photodynamic therapy (Ce6-PDT) showed anti-microbial and anti-inflammatory effects on acne vulgaris model previously. Excess sebum production in sebocytes is a crucial cause of acne. However, information on the effect of Ce6-PDT associated with lipogenesis in sebocytes has not been reported so far. The oil red O staining, triglyceride assay and cholesterol assay were used to investigate lipid synthesis in human sebocytes. The...