Fibroblast growth factor‐21 protects against fibrosis in hypertensive heart disease
Abstract
FGF21 is an endocrine factor that contributes to multiple pathophysiological processes, mainly via its action as a metabolic regulator and cardioprotective agent. Recent studies have shown increased circulating FGF21 levels in hypertensive patients and in mouse models of hypertension. However, the relevance of FGF21 in hypertensive heart disease has not been addressed. Hypertension was induced by treating 4-month old WT and Fgf21-/- mice with...
Paper Details
Title
Fibroblast growth factor‐21 protects against fibrosis in hypertensive heart disease
Published Date
Jan 30, 2019
Journal
Volume
248
Issue
1
Pages
30 - 40
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