Nutlin-loaded magnetic solid lipid nanoparticles for targeted glioblastoma treatment
Abstract
Glioblastoma multiforme is one of the deadliest forms of cancer, and current treatments are limited to palliative cares. The present study proposes a nanotechnology-based solution able to improve both drug efficacy and its delivery efficiency.Nutlin-3a and superparamagnetic nanoparticles were encapsulated in solid lipid nanoparticles, and the obtained nanovectors (nutlin-loaded magnetic solid lipid nanoparticle [Nut-Mag-SLNs]) were characterized...
Paper Details
Title
Nutlin-loaded magnetic solid lipid nanoparticles for targeted glioblastoma treatment
Published Date
Mar 1, 2019
Journal
Volume
14
Issue
6
Pages
727 - 752
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Notes
History